Main Role
- Roger KwokYeung Yat To / Dr. Yeung / "YT"Main Role
- Kenneth MaTong Ming / Dr. TongMain Role
- Moses ChanLee Man Shuen / Dr. Lee / "Vincent"Main Role
- Nancy WuIp Ching / Dr. IpMain Role
- Natalie TongSo Yee / Dr. So / "Zoe"Main Role
- Kelly CheungLui Oi Ning / Dr. Lui / "Yan"Main Role
Support Role
- Ram ChiangYu Cham Tam / Dr. Yu / "Samuel" [Man Shuen's boss]Support Role
- John Chan[Secretary of the Department of Health]Support Role
- Max CheungWan Ming Cheung / Dr. Wan / "Martin" [Hong Kiu's old husband]Support Role
- Virginia LauCheung Ting [Yat To's old wife]Support Role
- Willie WaiHo Chi Gwong / Dr. Ho / "Hugo" [Tong Ming's subordinate]Support Role
- Lesley ChiangFan Wai Shan / Dr. Fan /" Rachel"Support Role
- Osanna ChiuJeung Sin Wong / "Jackie"Support Role
- Alex YungSze To Kit / "Vincent"Support Role
- Doris ChowMa Wing Zi / Dr. Ma / "Paula"Support Role
- Aurora LiKiu Chi Yau / "Kate"Support Role
- Gary TamNg Sam YipSupport Role
- Amy Ng Support Role
- William Chu Support Role
- Keefe Ng Support Role
- Marktwo Lee Support Role
- Patrick LamLing Weikang / "Ben" [Assistant Consultant Neurosurgery]Support Role
- Willie Lau Support Role
- Kris Lam Support Role
- Carlos KooDr. Authur RichmondSupport Role
- King Lam[Members of the Legislative Council of Hong Kong]Support Role
- Athena Ng Support Role
- Au Hin WaiFung WingSupport Role
- Helen Seng Support Role
- William Chak Support Role
- Georgina ChanDr. WongSupport Role
- Justin Wong Support Role
- Kitterick Yiu Support Role
- Mark Ma Support Role
- Fei WongXu Xiao Yun / "Wendy" [ Resident doctor, subordinate of Ye Qing]Support Role
- Ng Pui Yu Support Role
- Kelvin Liu Support Role
- Elizabeth Nicole WuLau Kei Kei [Nurse in emergency room]Support Role
Guest Role
- Felix Ng Guest Role
- Sophie Yip Guest Role
- Andrea So Guest Role
- KC Wu(Ep. 12, 14)Guest Role
- Tony Chui Guest Role
- Arthur Sy Guest Role
- Janice Pang Guest Role
- Thomas Ng Guest Role
- Sheldon Lo Guest Role
- Hugo ChengCheung Ka Hin [Sick child] (Ep. 3-4)Guest Role
- Rosita Kwok(Ep.23)Guest Role
- Wiyona YeungAmanda [Hong Kong star]Guest Role
- Mina Kwok Guest Role
- Fanny Lee Guest Role
- GoGo CheungMa Suk Yin (Ep. 9-11)Guest Role
- Louis Szeto Guest Role
- Jacky Lee Guest Role
- Tse Ho Yat Guest Role
- Siu Lai Man Guest Role
- Michael Wai[Pediatrician] (Ep. 10-11)Guest Role
- Andy Lau[Pediatrician]Guest Role
- Lucas Yiu Guest Role
- Yuki LawFong Man (Ep. 2-4)Guest Role
- Cayley Mak Guest Role
- Alan Tam Guest Role
Unknown
- Andy Wong Unknown
- Marco Lee Unknown
- Wu Fei Unknown
- Irina Tang Unknown
- Blossom Chan Unknown
- Venus TangLam Ka MeiUnknown
- Ball Mang Unknown
- Jan Tse Unknown
- Matthew ChuAndyUnknown
- Darren Wong Unknown
Bit part
- Clementine SzeMV Main Girl [Ep15]Bit part
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